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As a result, SGLT2 inhibitors are now recommended as first add-on (or even first-line, alongside metformin) when someone has established cardiovascular disease, heart failure, or chronic kidney disease: even if their HbA1c is at target
a , Individual sgRNA scores of SLC25A40 and TXNRD2 from the CRISPR screens in indicated cell lines from Fig
In spite of increasing overall prevalence of conditions that contributed to the pathophysiology of HFpEF, there was considerable international variation in the prevalence of HFpEF and its contributing factors
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