GIP (glucose-dependent insulinotropic polypeptide) further enhances insulin sensitivity and may directly influence fat metabolism in adipose tissue
Presented for research literature review only Harman AW et al
The most significant marker, considered a gold standard, was F2-isoprostane and this was significantly more reduced by oral Acetylglutathione than with the IV glutathione.[11],[12] Oral S-Acetyl Glutathione, dosed 200mg daily for 7 days, AM IV 1400mg, single dose Serum and urine tested after 1 week of administration N=6, (4 female, 2 male, average age 45) Markers chosen are measures of Antioxidants F2-Isoprostane is the Gold Standard of oxidative stress markers Conclusion: Oral S-A GSH compares favourably to a one-time, equivalent dose of IV administered Glutathione GSH : Blood levels are lower in the A-GSH group as compared to the IV group because the A-GSH is being taken up by the cell.[13] This is substantiated by the following markers: F2-Iso : (F2- isoprostane ) measurement of redox status and oxidative stress

Reduced Glutathione (L-Glutathione), the most powerful antioxidant, reduces oxidative stress, reduces cell damage in alcoholic & nonalcoholic fatty liver disease, & improves insulin resistance