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Preclinical studies have explored possible mechanisms including improved endothelial function, reduced inflammation, and potential anti-atherosclerotic properties, though these effects require further investigation in humans before definitive conclusions can be drawn

Small routines like taking stairs, short walks, or stretching during breaks are useful

These structural changes extend the drugs activity in the body, enabling less frequent dosing while maintaining its therapeutic effect

Several analyses have not found a significant overall increase in thyroid cancer risk, and newer reviews suggest that some early diagnoses may reflect detection bias rather than a true causal effect