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Short answer: It appears tolerable in very limited early human data, but there is not enough evidence to call it safe for general use
This is why BPC-157's perception as a 'systemic recovery peptide' grew within biohacking and peptide communities
A prodrug nanoparticle synthesized by conjugating PD-L1Pep-2 with doxorubicin via cathepsin B-cleavable peptide linker (FRRG) inhibited tumor progression in the 4T1 mouse breast tumor model by inducing doxorubicin-mediated immunogenic cell death and blocking PD-L1 through PD-L1Pep-2 102
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