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SAM, in turn, provides methyl for the synthesis of DNA, fatty acids, phospholipids and proteins, with methylation of myelin proteins maintaining the stability of the myelin sheath
Second, the doses are small because the target is a high-affinity intracellular enzyme, not a receptor that needs saturating with milligrams of drug
Possible Side Effects Yes
The authors found that GLP-1 RA use was associated with a significantly decreased risk of developing dry AMD compared with patients taking metformin (HR = .68), insulin (HR = .72), and statins (HR = .70)
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