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In humans it is synthesized in the liver, kidney, and brain and actively transported to other areas of the body
The peptide is posited to engage with G-protein coupled receptors, which may increase intracellular calcium levels
During GLP-1 treatment, some patients experience sleep disruption or insomnia as side effects
Physiological functions [edit source] GLP-1 possesses several physiological properties making it (and its functional analogs) a subject of intensive investigation as a potential treatment of diabetes mellitus, as these actions induce long-term improvements along with the immediate effects
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