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found defective insulin levels and impaired PI3K/AKT/mTOR signaling pathways in the ovary and endometrium of patients with PCOS ( 2 O 2 -induced oxidative stress and autophagy levels in FGCs, via the PI3K/AKT/mTOR signaling pathway (Xu et al., 2022)
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They cannot regenerate follicles that have been completely destroyed
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