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Both injectable and oral formulations are approved for this use

Mechanistically, these neuroprotective effects are underpinned by the activation of canonical GLP-1 R signaling pathways within the retina

Am J Pathol 2009

(2015) reported results from a Phase 3 clinical trial of afamelanotide in erythropoietic protoporphyria, demonstrating increased time to phototoxicity symptoms and supporting regulatory approval [2]