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CARDIOVASCULAR HEALTH: Helps support heart health and cardiovascular function
Support for clinical significance came from a responder analysis based on an anchored assessment, which evaluated participants perception of benefit
In non-obese diabetic (NOD) mice which are a murine model of T1DM, GLP-1RAs can improve immune functions and inflammatory responses as well as mitigating against islet cell damage, an action which may be related to the decrease in the expression of miR-19b [145]
however, these benefits are compromised by PPAR-mediated side effects, primarily weight gain
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