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Hederagenin improves renal fibrosis in diabetic nephropathy by regulating Smad3/NOX4/SLC7A11 signaling-mediated tubular cell ferroptosis

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Aunque bien tolerado en la mayora de los casos, puede producir efectos adversos , por lo que es imprescindible un seguimiento mdico especializado

Over the last few years, several regulatory authorities, such as the FDA and EMA, reported the incidence of mood alterations, depressive symptoms, and even suicidal thoughts with the use of GLP-1 receptor agonists during the pharmacovigilance surveillance process, which raises the issue of their psychiatric safety [13,14,15]