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In adults with type 2 diabetes, semaglutide, a GLP-1 receptor agonist, has drawn interest for its capacity to enhance glycemic control, lowering episodes of hyperglycemia and promoting weight reduction

This oral daily regimen offers the same ~15% weight loss seen in the Wegovy data submitted to the FDA

[1] [2] Patients with a history of diabetic retinopathy require careful consideration, as the SUSTAIN-6 trial identified a higher incidence of retinopathy complications in the semaglutide group, particularly in those with pre-existing retinopathy and rapid improvement in blood glucose control

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