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These toxins lead to disruption in the roles of cytochrome P450 (CYP450) in xenobiotic detoxification and activation, changes in CYP450 expression and related genes can significantly affect xenobiotic potential risk (10)
GLP-1 receptor agonists reduce mortality in lower-risk patients, although absolute benefits are smaller
L., Hofer, K., Nubel, G
In this broader context, the presence of an active protease in the cytosol acts as an endogenous danger signal that triggers lytic cell death and immune responses
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