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Numerous studies have confirmed that EDCs exposure is a significant environmental risk factor and determinant of POI [282]
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To highlight just a couple, their ASC30 small molecule that offers ultra long-acting potential with monthly dosing options and potentially even quarterly maintenance dosing
Notably, the buccal cavity allows prolonged drug residence time without frequent mucus clearance or rapid tissue metabolism, providing sufficient duration for transmembrane drug permeation and steady absorption
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