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These studies evaluated FDA-approved branded medications under controlled conditions, not compounded formulations

CMS did not offer an explanation Friday for its decision, and federal spokespeople did not immediately respond to requests for comment

A pooled analysis across all SURMOUNT trials showed that 92.7% achieved at least 5% weight loss, 84.4% hit 10%, 73.6% reached 15%, 56.1% achieved 20%, and 38.7% made it to 25%