While adverse event reports do not establish causation (the events may have been caused by factors unrelated to the compounded medication), the volume of reports signals a need for heightened caution
Hypoglycaemia: Whilst these agents are not expected to cause low blood sugar on their own, people with diabetes who are also taking insulin or sulfonylureas may be at increased risk of hypoglycaemia
Shah, V
Afr J Biotechnol 10:634863 Cuadrado A, Garcia-Fernandez LF, Gonzalez L, Suarez Y, Losada A, Alcaide V, Martinez T, Fernandez-Sousa JM, Sanchez-Puelles JM, Munoz A (2003) Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK