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Preliminary double-blind, placebo-controlled studies demonstrated the efficacy of melanotan in inducing penile erection in men with erectile dysfunction, although in a very restricted population.Unfortunately, there are no experimental data on the mode of action of melanotan II, as melanotan II is the first -MSH agonist inducing penile erection when injected peripherally
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From there, the islets were placed into 2 ml Eppendorf tubes and frozen at 80 C in TRIzol (Invitrogen) for RNA analysis
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