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5E, F and Supplementary Fig
Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks
Measurement of Malondialdehyde Level The degree of lipid peroxidation can be analyzed by quantification of MDA
Because body types vary, some people will lose weight faster than others, but in general, most people report losing about 2 to 3 pounds per week
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