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cDNA was synthesized using Superscript III First-Strand Synthesis System (Invitrogen, Carlsbad, CA) according to manufacturers instructions using 1 g total RNA in a 20 l reaction volume

3.1% placebo STEP-1 weight loss / 14.9% mean body weight reduction at 68 weeks with semaglutide 2.4 mg vs

Supplemental Figures and Legends Funder Information Declared Footnotes ** Co-Senior Authors Conflict of Interest Statement: DBR is an employee of Novo Nordisk

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