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Reduced GSH availability, whether due to metabolic dysregulation or chronic ROS exposure impairs the redox buffering capacity of immune cells
"Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents"
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The Tim-3/Gal-9 pathway also inhibits the function of macrophages and downregulates the release of inflammatory factors
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