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"Amylin Receptor Agonists: Mechanisms of Action in Metabolic Disease." Nature Reviews Endocrinology, 2023, 19(8): 467-481
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A phase 3 trial (the final set of trials before a drug manufacturer seeks FDA approval) in adults with obesity or overweight and at least one obesity-related complication found that CagriSema helped participants lose an average 20.4% of their body weight at 68 weeks of treatment, compared with 3% in the placebo group
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