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It also helps reduce appetite and supports weight management
If 12-15 million patients are using GLP-1 drugs by 2030 it would equate to a 1.8% headwind to caloric intake
It is noteworthy that exendin-4 (Ex-4), a peptide derived from the saliva of the American Gila monster, exhibits pharmacological functions similar to those of GLP-1 and is resistant to DPP-4 degradation
From 2008-2010, Sanofi-Aventis Acomplia (selective CB1 antagonist) and Abbott Laboratories Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns
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