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discard if accidentally frozen Expiration monitoring Track reconstitution dates and discard after recommended timeframes Proper handling extends beyond storage
A vital factor in these patients is iron overload, although when present, it can be effectively managed by chelation therapy (Berdoukas 2012)
Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)
In cases where the medication cannot be withheld, patients can either have a gastric ultrasound to evaluate residual gastric volume, or they can be assumed to have a full stomach
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