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In SURMOUNT-4 (Aronne et al., *JAMA* 2024), all patients ran an open-label phase reaching maximum tolerated dose (10 mg or 15 mg weekly) for 36 weeks, losing an average of 20.9% of body weight in that phase
By regulating blood sugar levels and improving insulin sensitivity, GLP-1 injections also help curb sugar and carb cravings, which are common triggers for overeating
Similarly, 12 weeks of aerobic and resistance training increased NAMPT levels in skeletal muscle
The FDA states on its personal importation page that "in most circumstances, it is illegal for individuals to import drugs or devices into the U.S
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