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2011) examined miR-122 and miR-192 in APAP-induced acute liver injury patients ( n = 53) and showed that both miRNAs were elevated (Table 1)
eLife, 2015
While these studies confirm the existence of ferroptosis and oxidative accumulation, the specific and complex mechanism remains to be fully elucidated
Future research should focus on optimizing the dose, bioavailability, and long-term effects of C3G, and exploring its interaction with gut microbiota to pave the way for novel dietary or pharmacological strategies enhancing metabolic health in T2DM
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