The researchers injected a randomized group of male vervet monkeys with either "escalating doses" (up to 0.05 mg/kg) of the semaglutide GLP-1 agonist or a placebo twice weekly for two weeks
The prices of these medications vary depending on whether youre prescribed the brand-name or generic version, your location, preferred pharmacy, and insurance coverage
Study endpoints include epithelial-barrier function, tight-junction protein expression, inflammatory signaling, and mucosal tissue remodeling in models of intestinal inflammation, increased permeability, and chemically induced gastrointestinal injury
However, 4% reported unknown side effects of reproductive symptoms, including intermenstrual bleeding, heavy bleeding, and irregular menstrual cycles