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Mushrooms Not all mushrooms are adaptogens, but the ones that are (called functional mushrooms) can provide health benefits such as improved memory, focus, and mood.5 Codeage again stands apart from our other recommendations by having such mushrooms in its "Deep Blue Mind Enhancing Blend: Cordyceps,37 reishi,38 and lion's mane, all of which have the potential to help with depression and anxiety.39 Saffron While it's better known as the world's most expensive spice, saffron has been shown to possess antidepressant effects similar to prescription medications but with fewer side effects, per the authors behind one 2018 review.40 In addition, some research shows that it can improve sleep quality and duration.7 Innerbody Labs Sleep Support is our only top recommendation to contain saffron, and its 30mg dose is within the range used in most reviewed studies.7 In fact, its 30mg dose is the exact amount used in a 2006 study that saw improvements in measures of mild-to-moderate depression.7 41 Saffron also features in one of our honorable mentions: Ritual Stress Relief