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The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers

By blocking NNMT, 5-Amino-1MQ preserves the NAD+ precursor pool and intracellular SAM (the universal methyl donor), effectively closing a metabolic drain that accelerates fat storage and cellular aging

These FDA-approved peptides work the same way regardless of sex by mimicking the GLP-1 hormone to reduce hunger and cravings, per GoodRx, though a provider should still tailor dosing to an individual's health history and goals