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BRIN-BD11 cells were used throughout this study for their well characterised responses to multiple stimuli, cell culture based convenience and their established intact response to GLP-1R activation both in terms of cAMP and resulting stimulated insulin secretion 36, 37

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2025;48(1 Suppl 1):S181-s206

Studies have shown that patients with HF have significant changes in amino acid levels, especially in the oxidative capacity of branched-chain amino acids, leading to impaired cardiac energy metabolism (145)