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Its primary appeal lies in its ability to optimize fuel usage at the cellular levelmaking it highly relevant for fat loss, endurance, and aging

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mTOR inhibition with rapamycin (sirolimus) robustly induces autophagy, reducing tau and amyloid- aggregation in AD models as well as mutant huntingtin in HD models

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Extended wakefulness, exposure to cold, excessive noise).

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However, specific chemotherapeutic agents can induce immunogenic cell death (ICD), characterized by the release of damage-associated molecular patterns (DAMPs) that prime antitumor T cell responses (43, 44)

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