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On the next day, mice were given a single dose of oral gavage of 2.5 g/kg b.wt
doi:10.1186/1742-4933-2-17
The medication forms a depot in the fatty tissue and gradually releases into circulation over several days
In the SURMOUNT-2 study, which involved 938 adults with obesity or overweight and T2D, tirzepatide showed significant weight loss effects of 13.4% and 15.7% for the 10 and 15 mg doses, respectively, with over 80% of participants experiencing at least a 5% weight loss [92]
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