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doi: 10.1016/j.cell.2019.05.054

Balancing the structural robustness required to prevent premature drug leakage in systemic circulation with the necessity for stimuli-responsive disassembly at the tumor site remains a critical engineering challenge

The question is not if this will happen

While some foods like spinach, avocados, and asparagus contain glutathione, the amount is relatively small and much of it is lost during cooking or digestion