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Phenotypic screening is the pragmatic alternative: apply the peptide to a relevant cell system and measure broad outputs, transcriptome by RNA-seq, proteome, or metabolic and viability panels, without presupposing a target

Multiple comparisons were analysed using one-way analysis of variance or two-way analysis of variance followed by Dunnetts post hoc test

In OA and other inflammation-related diseases, NF-KB activation commonly leads to decreased transcription of antioxidant factors such as GPX4, NQO1, and HMOX1, thereby promoting ferroptosis (124, 125)

This device could also be considered for use in specialized research of skin characteristics even with a small sample size