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Maintenance phase: Continued use along with sun or sunbed sessions is said to help deepen and maintain the tan
Symptomatologic improvement was greater in patients younger than 6 years of age as compared to those who began supplementation at an older age, though, this study was a case series of 20 patients, further randomized controlled trials are needed
Regulatory update (August 2026): PCAC voted to recommend TB-500 for the 503A Bulk Drug Substances List at the July 23, 2026 hearing, overriding FDA staffs own recommendation
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