Nevertheless, in a network meta-analysis comparing short-acting and long-acting GLP-1RAs when used in conjunction with basal insulin, long-acting GLP-1RAs resulted in significantly greater reductions in glycated hemoglobin (HbA1c), fasting plasma glucose, and body weight compared to short-acting GLP-1RAs, with better gastrointestinal tolerability [15]
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Each hormone was independently divided into low, intermediate, and high tertiles (a statistical division of a dataset into three equal parts) based on its distribution within the study population
Patients commonly experience gastrointestinal side effects including nausea, vomiting, diarrhea, and constipation, which may further compromise nutritional status