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No longer constrained by the Woodward-Hoffmann selection rules that govern pericyclic transformations, we then extended the methodology to include (3 + 2) annulation reactions in which the dienes were substituted by styrenyl substrates (total 4e ) to furnish cyclopenta[ b ]indoles
95% CI, 1.05-1.47), although these findings were based solely on unadjusted estimates
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