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Adults who have a BMI index of 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or greater (overweight) with at least one weight-related health problem (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia) may benefit from GLP-1 injections combined with physical activity and a reduced calorie diet [11]
JoVE (2020)
This technology can be applied to create genetically engineered bacteria which possess the ability to produce the GLP-1 protein once ingested orally
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