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But that is not the whole story
These processes play key roles to promote chemoresistance in tumors, where elevated GSH inactivates electrophilic chemotherapeutic agents (cisplatin, alkylators), GSTs enable drug conjugation, and MRP-catalyzed efflux reduces intracellular drug levels - while inhibiting therapy-induced oxidative stress at the same time
Burstein HJ, Lacchetti C, Anderson H, Buchholz TA, Davidson NE, Gelmon KA
Label and Refrigerate Write the date, concentration (e.g., "10mg/mL"), and a discard date (28-60 days) on the vial
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