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Bai Z, Wang Z

1 Introduction Acute Mountain Sickness (AMS) is a common and potentially debilitating condition that affects individuals ascending to altitudes above 2,500 m above sea level ( 2 ), a condition known as hypobaric hypoxia ( Notably, studies have established that exposure to hypobaric hypoxia promotes a redox imbalance, leading to an exacerbated increase in reactive oxygen species (ROS) along with deterioration of endogenous antioxidant defenses ( 2 O 2 ) in exhaled breath condensate (EBC), both at rest and during exercise at altitude, correlating with decreased arterial oxygen saturation and AMS symptom severity ( Based on these findings, various studies have proposed antioxidant use as a preventive therapeutic strategy, given that the only pharmacological treatment currently employed to mitigate AMS is acetazolamide, along with anti-inflammatory agents such as dexamethasone and ibuprofen

Swimmer Cody Miller left Abu Dhabi two weeks after the Iran war began for a planned break to visit his family and stayed home to train in Las Vegas

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