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The inhaled silica particles can be directly phagocytosed by alveolar macrophages (AMs), and thereby triggers NLRP3 inflammasome activation and IL-1 production, which results in a cascade release of proinflammatory and profibrotic cytokines, i.e., IL-6, tumor necrosis factor (TNF-) and TGF-1

Thymosin beta 4 and Fx, an actin-sequestering peptide, are indistinguishable

[18] Other research suggests that several pharmaceutical companies, including AstraZeneca, Zealand Pharma, Roche, and Amgen, are expected to enter the GLP-1 market, with multiple drug launches planned between 2027 and 2032

Read Ipsos latest PoV, where we explore these topics in more depth: Ipsos has tracked MASH treatment since 2017