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Destruction of mitochondrial ETC leads to increased ROS production, which triggers matrix metalloproteinases (MMP) induction, ultimately leading to compromised BBB integrity
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Overall, the findings suggest potential benefits of GLP-1RA treatment in this high-risk population, although residual confounding and heterogeneity across autoimmune diseases mean the results should not be interpreted as proof of causality
The efficacy and safety of dipeptidyl peptidase-4 inhibitors for type 2 diabetes: A Bayesian network meta-analysis of 58 randomized controlled trials
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