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For the derivatization with pyridine-3-sulfonyl chloride, 80 l of sodium bicarbonate buffer (0.1 M, pH 10) and 80 l of pyridine-3-sulfonyl chloride (2 mg ml 1 in acetone) were added to the dried extracts
Sikiric, P., Drmic, D., Sever, M., Klicek, R., Blagaic, A
Not only are these treatments expensive, but they require multiple weekly trips to the doctor to administer (results only last a period of time), pose risks with repeated IV procedures, and are not patient friendly
at this point only a few early stage clinical trials are taking place worldwide
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