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The active region of TB-500 binds to G-actin monomers, facilitating the reorganization of the cellular cytoskeleton

The variable R group gives rise to the four most commonly known cobalamins: cyanocobalamin (CNCbl), methylcobalamin (MeCbl), adenosylcobalamin (AdCbl, also known as cobamamide or 5-deoxyadenosylcobalamin), and hydroxocobalamin (OHCbl)

In vitro studies characterise its effects on decorin expression, fibronectin production, and gene expression profiles associated with extracellular matrix biology

How it works: Epitalon is a synthetic version of epithalamin, a substance from the pineal gland studied by Russian gerontologist Vladimir Khavinson