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Carew LB, Evarts KG, Alster FA

"We have long been believers that clinicians should turn to a variety of drugs, devices, and procedures in the treatment of diseases." In April, top-line data from Eli Lillys phase III SURMOUNT-OSA trial comparing the efficacy of GLP-1s alone and in combination with positive airway pressure (PAP) in OSA patients over 12 months

But the argument is that a slower start with better adherence ultimately produces better outcomes than a faster start that triggers side effects severe enough to cause missed doses or protocol abandonment

Intrauterine devices (IUDs) that release progestin, such as the levonorgestrel-releasing IUS, are used primarily to control heavy menstrual bleeding associated with fibroids