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Individual results vary based on dose, adherence, starting weight, diet, activity, and individual biology
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Chromatographic and MS methods have already achieved relative maturity in this domain
Reduced-frequency GLP-1 as a maintenance strategy: in this case series, patients who tapered from weekly semaglutide/tirzepatide to less frequent dosing maintained weight loss, body composition, and metabolic syndrome gains, supporting structured de-escalation to lower burden
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