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It activates one of the body's master regulators of metabolism, an enzyme called AMP kinase, triggering some of the same benefits that fasting and exercise provide to our cells
The exact cause is unknown, but RLS can be linked to problems with dopamine signaling in the brain, genetic factors, iron deficiency, kidney disease, and certain medications
Studies such as the LEADER trial (liraglutide), SUSTAIN-6 (semaglutide), and REWIND (dulaglutide) have shown reductions in major adverse cardiovascular events, including heart attack and stroke, in people with type 2 diabetes and established cardiovascular disease or high cardiovascular risk
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