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GLP-1 RAs were identified in the DRUG files using generic or brand names, including exenatide (BYETTA, BYDUREON BCISE), liraglutide (VICTOZA, SAXENDA, XULTOPHY), lixisenatide (LYXUMIA, ADLYXIN, SOLIQUA), dulaglutide (TRULICITY), semaglutide (OZEMPIC, RYBELSUS, WEGOVY), and tirzepatide (MOUNJARO, ZEPBOUND)

There is one Phase I trial registered as NCT02637284 in 2015, intended to enrol forty-two participants, which was subsequently cancelled with no published results [7]

Application 13.2.5

While ARA-290 has shown no tumor-promoting effects in studies, its tissue-protective properties theoretically could affect cancer cells