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Some of the patients had surgery, some avoided surgery

(2013) 98:E116372

Indeed, several studies have demonstrated that aberrant IGF signaling plays a critical role in the pathogenesis and progression of several types of cancer, including lung, breast, colon, prostate, ovary, pancreas, and thyroid ( Nevertheless, data coming from observational studies are still conflicting and inconclusive, since some authors observe an association between insulin therapy and increased cancer risk (Tseng, 2019

Experts also point out that there have been no placebo-controlled clinical studies in this population to date and more quality research is needed