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Hard criteria can be described as feasibility results, incidence of condition/disease, country/site track record of recruitment in particular indication, investigator experience, country healthcare system peculiarities (e.g., reimbursed medicines, access to certain therapies), costs of clinical trial conduct in the country, etc
Because for most Americans, suboptimal health today leads to a higher risk of chronic disease tomorrow
These findings suggest the systemic effects of GLP-1RA could be useful to manage multiple comorbidities targeting both skin and metabolic components
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