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Variants of OXM resistant to DPP-IV (achieved by addition of PEG [86], fatty acids [87], substitution of certain amino acids [85] or even combined modifications [88]) have been advanced to circumvent the limited clinical potential of the native peptide
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Pharmacological options for weight management in patients meeting eligibility criteria include: Orlistat : A lipase inhibitor that reduces dietary fat absorption, available through NHS prescription for patients with BMI 28 kg/m with comorbidities or 30 kg/m without
Gonzalez-Rellan, M
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