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Gates 1999) The efficient formation of hydroxyl radicals is achieved when stoichiometric quantities of redox metals are present and when a reducing agent (O 2 ) that can recycle metal ions back to their active reduced form is present (Valko et al

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SCFAs can travel through the gut-brain axis, across the bloodbrain barrier into the central nervous system, and affect the cellular biological mechanism of neural development, thereby resulting in various physiological processes in the liver, including gluconeogenesis, insulin sensitivity, and adenosine 5-monophosphate activated protein kinase (AMPK) activity (53, 54)